Sunday, March 1, 2015

British Journal of Clinical Pharmacology: Ketamine analgesia is limited by low intrinsic efficacy compounded by large interindividual variability in drug responses, possibly due to the heterogeneity in drug concentration.

4. CYP2B6*6 allele and age substantially reduce steady‐state ketamine clearance in chronic pain patients: impact on adverse effects

Date: Feb 23, 2015
Abstract Aim Ketamine analgesia is limited by low intrinsic efficacy compounded by large interindividual variability in drug responses, possibly due to the heterogeneity in drug concentration. The CYP2B6*6 allele is associated with substantially reduced ketamine metabolism in vitro, and therefore, may affect ketamine clearance. Our aims were to examine the impact of the CYP2B6*6 allele on ketamine plasma clearance, and on adverse...more

Teaching NY Veterinarians About Legal vs. Illegal Compounding

HVVMS CE Session: Pharmaceutical Compounding Regulations for Practicing Veterinarians in NY

3/11/2015
When: 3/11/2015
7 to 9 p.m.

Where: Map this event »
Ramada Fishkill
542 Route 9
Fishkill, NY 12524
Presenter:
Marc Gustas and Rosella Menta, Rye Beach Pharmacy
Contact:
Keith Sobel, DVM, DACVIM
keithsobel@gmail.com
Phone: 301.518.3859



Details



Veterinary attendees will learn the specific regulations that control the compounding industry.

These regulations address, among other things:
Manufacturing vs. office use
Shipments from out of state
Injectables
Factors that dictate why a medication can or cannot be compounded
more information

Sterile compounding: Pharmacy profession should take back control: author notes accountability is not something you can outsource!

Second Question of the Day March 1, 2015 What exactly would it take not to be granted a pharmacy licence from the Texas Board of Pharmacy

APPLICANTS FOR PHARMACY LICENSE Concierge Compounding Pharmaceuticals, Inc., Applicant for Pharmacy License, Henderson, NV. Alleged violation: corporate officer convicted (in 2001) of the felony offense of Conspiracy to Commit Securities Fraud. Agreed Board Order accepted by applicant and entered by the Board on 08-06-13: pharmacy license granted and placed on 1-year probation with conditions. University Medical Center East Pharmacy, Applicant for Pharmacy License, El Paso, TX. Alleged violation: failure to disclose criminal history of a corporate officer on pharmacy licensure application. Agreed Board Order accepted by applicant and entered by Board on 03- 01-13: pharmacist license granted and fined $1,000. Wylie Pharmacy, Applicant for Pharmacy License, Wylie, TX. Alleged violation: failure to disclose criminal history of a corporate officer on pharmacy licensure application. Agreed Board Order accepted by applicant and entered by Board on 03- 06-13: pharmacy license granted and fined $1,000. Cardinal Health 414, LLC, Applicant for Pharmacy License, Denver, CO. Alleged violation: disciplinary action taken by the Colorado State Board of Pharmacy. Agreed Board Order accepted by applicant and entered by Board on 04-12-13: pharmacy license granted and reprimanded.

quoted from Texas Board of Pharmacy Winter 2014 Disciplinary Newsletter

Texas Board of Pharmacy November 2014 Meeting Minutes Finally Posted in February 2015