Wednesday, March 26, 2014

FDA Enforcement Report Week of March 26, 2014 for Drugs

Drugs Clalis capsules, 50 mg, 6 -count bottle ( labeling is in foreign language) All lots Class I Marketed without an Approved NDA/ANDA: Laboratory analysis conducted by the FDA has determined that the products was found to contain sildenafil, an undeclared active pharmaceutical ingredient. Fabscout Entertainment, Inc
Drugs Silver Sword capsules, 180 mg, 16-count clamshell tin, UPC 1 234658 970128 12345 (labeling is in foreign language) All lots Class I Marketed without an Approved NDA/ANDA: Laboratory analysis conducted by the FDA has determined that the products was found to contain sildenafil, an undeclared active pharmaceutical ingredient. Fabscout Entertainment, Inc
Drugs Marcaine (bupivacaine HCl) injection, USP, 0.25%, 30 mL single-dose vials-preservative free, packaged in 10-count vials per carton, Rx only, Hospira, Inc., Lake Forest, IL 60045, NDC 0409-1559-30. Lot 25-220-DD, Exp 1JAN2015 Class I Presence of Particulate Matter: Units of this lot may have visible metal particles embedded in the vial and in the solution causing the product to be discolored. Hospira Inc.
Drugs 5% Dextrose Injection, USP, 100 mL Single dose VIAFLEX plastic containers, Rx only, Baxter Healthcare Corporation, Deerfield, IL 60015 USA, Product code 2B0089, NDC 0338-0017-38. Lot #: P285288, Exp 11/13 Class I Baxter is issuing a voluntary recall for these IV solutions due to particulate matter found in the solution. Baxter Healthcare Corp.
Drugs 0.9% Sodium Chloride Injection, USP, packaged in a) 50 mL Single dose VIAFLEX plastic containers (Product code 2B1308, NDC 0338-0049-31) and b) 100 mL Single dose VIAFLEX plastic containers (Product code 2B1302, NDC 0338-0049-18) and (Product code 2B1309, NDC 0338-0049-38), Rx only, Baxter Healthcare Corporation, Deerfield, IL 60015 USA. Lot #: a) P297283, Exp 08/14; b) P292326, Exp 04/14; P293993, Exp 05/14; and P293514, Exp 04/14 Class I Presence of Particulate Matter: Baxter is issuing a voluntary recall for these IV solutions due to particulate matter found in the solution. Baxter Healthcare Corp.
Drugs Clinimix 4.25/25 sulfite-free (4.25% Amino Acid in 25% Dextrose) Injection, 1000 mLCLARITY Dual Chamber Container bag, Rx only. Dist: Baxter Healthcare Corporation, One Baxter Parkway, Deerfield, IL 60015. NDC: 0338-1115-04. Lot#: P287045, Exp 6/2014 Class I Presence of Particulate Matter: Particulate matter includes wood, sodium citrate and dextrose. Baxter Healthcare Corp.
Drugs Clinimix E 4.25/10 sulfite-free (4.25% Amino Acid with Electrolytes in 10% Dextrose with Calcium) Injection, 2000 mL CLARITY Dual Chamber Container bag, Rx only. Dist: Baxter Healthcare Corporation, One Baxter Parkway, Deerfield, IL 60015. NDC 0338-1115-04. Lot#: P275883, Exp 10/2013 Class I Presence of Particulate Matter: Particulate matter includes wood, sodium citrate and dextrose. Baxter Healthcare Corp.
Drugs Clinimix 5/15 sulfite-free (5% Amino Acid in 15% Dextrose) Injection, 2000 mL CLARITY Dual Chamber Container bag, Rx only. Dist: Baxter Healthcare Corporation, One Baxter Parkway, Deerfield, IL 60015. NDC: 0338-1099-04. Lot# P285122, Exp 5/2014 Class I Presence of Particulate Matter: Particulate matter includes wood, sodium citrate and dextrose. Baxter Healthcare Corp.
Drugs Hydroxyprogesterone Caproate 250mg/ml in Sesame Oil, 1 ml injectable solution, in 3 ml single dose syringes; a multi-ingredient compounded medication in bulk, containing Benzoyl Benzoate USP 0.46 ml/1ml, and Benzyl Alcohol 0.02 ml/1ml; syringe is labeled in part ***FOR INJECTION USE ONLY***RX South LLC DBA RX3 12230 Iron Bridge Rd Chester, VA 23831*** Lot number: 12052013:03 Expiration date: 06/03/2014 Class II Crystallization; visible crystals from the active ingredient formed due to extreme cold temperatures during shipping RX South LLC DBA RX3 Pharmacy
Drugs Advil PM Caplets, (Ibuprofen, 200 mg /Diphenhydramine citrate, 38 mg) 120 count bottle, OTC, Pfizer, Madison, NJ 07940 USA. NDC 0573-0164-43 G85041 Class III Subpotent Drug: This lot is being recalled because of out-of-specification test results for Diphenhydramine citrate. Pfizer Us Pharmaceutical Group
Drugs Guaifenesin USP, 50 Kg Drums, CAS No. 93-14-1, Reg. No. 05436, Caution: For Manufacturing, Processing, or Repacking, Delta Synthetic Co., Ltd. 15, Minsheng St., Tucheng Dist., New Taipei City, 23679, Taiwan (ROC), NDC 60203-1001 211J3291 211J3292 211K3293 211K3294 211K3295 211K3297 211K3298 211K3299 211K3301 211K3302 211K3315 211K3321 211K3322 Class II Presence of Foreign Matter: Guaifenesin API powder is being recalled due to the possibility that the product contains polyethylene fibers from a screen used to sift the Guaifenesin. Traxx International Corp
Drugs Daytrana (methylphenidate) transdermal system patch, Delivers 20 mg over 9 hours (2.2mg/hr), 1 patch per pouch , packaged in 30-count patches per box, Rx Only. Manufactured for Noven Therapeutics, LLC, Miami, FL 33186, By Noven Pharmaceuticals, Inc., Miami, FL 33186. NDC 68968-5554-3. Lot #69618, Exp. 09/14 Class II Defective Delivery System: Out of Specification (OOS) results for the z-statistic value, which relates to the patients and caregiver ability to remove the release liner from the patch adhesive prior to administration, were obtained. Noven Pharmaceuticals, Inc.
Drugs Daytrana (methylphenidate) transdermal system patch, Delivers 30 mg over 9 hours (3.3mg/hr), 1patch per pouch , packaged in 30-count patches per box, Rx Only.Manufactured for Noven Therapeutics, LLC, Miami, FL 33186, By Noven Pharmaceuticals, Inc., Miami, FL 33186. NDC 68968-5555-3. Lot #70132, Exp. 09/14 Class II Defective Delivery System: Out of Specification (OOS) results for the z-statistic value, which relates to the patients and caregiver ability to remove the release liner from the patch adhesive prior to administration, were obtained. Noven Pharmaceuticals, Inc.
Drugs Perrigo, Clindamycin Palmitate Hydrochloride for Oral Solution, USP, 75mg/5mL, 100 ml, NDC 0574-0129-01 2013313915 Exp 08/15, 2013374398 Exp 09/15, 2013323969 Exp 08/15, 2013364336 Exp 09/15, 2013323971 Exp 08/15, 2013364334 Exp 09/15, 2013313913 Exp 08/15 Class II Presence of Particulate Matter Perrigo is recalling seven lots of Clindamycin Palmitate Hydrochloride for Oral Solution 75mg/5ml. Paddock Laboratories, LLC
Drugs Venlafaxine Hydrochloride, Extended Release Capsules, 150 mg, UD-100 Tablets per Box (10 x 10), Rx Only, Manufactured by: Teva Pharmaceuticals USA, 1090 Horsham Rd, North Wales, PA 19454, NDC 63739-0512-10 Lot #: 91357 Class III Failed Dissolution Specification: Out of Specification dissolution results at 12 month interval. McKesson Packaging Services

RX south LLC dba RX# Pharmacy--

Hospira, Inc. Particles in vial

Drugs Marcaine (bupivacaine HCl) injection, USP, 0.25%, 30 mL single-dose vials-preservative free, packaged in 10-count vials per carton, Rx only, Hospira, Inc., Lake Forest, IL 60045, NDC 0409-1559-30. Lot 25-220-DD, Exp 1JAN2015 Class I Presence of Particulate Matter: Units of this lot may have visible metal particles embedded in the vial and in the solution causing the product to be discolored. Hospira Inc.

Pain Medicine News - Does Bill Have the Muscle To Stop Another NECC?

Pain Medicine News - Does Bill Have the Muscle To Stop Another NECC?

Oklahoma Told It Can’t Shield Suppliers of Execution Drugs

An Oklahoma judge ruled on Wednesday that the state could not keep secret the identities of the suppliers of lethal-injection drugs, raising doubts about the executions of two prisoners next month and fueling a growing legal battle in several states over secrecy in methods of execution.
The state argued that a supplier-secrecy law, passed in 2011, was necessary because of a shortage of execution drugs and threats against companies that supply them. But lawyers for the two prisoners, Clayton Lockett and Charles Warner, countered that without knowing the source of the drugs, courts could not determine whether the execution protocol satisfied the constitutional ban on cruel and unusual punishment, and prisoners were denied the right to know, and potentially question, how they would be put to death.
Judge Patricia Parrish, of the Oklahoma County District Court, declared the secrecy statute to be an unconstitutional violation of due process in an oral decision from the bench.
continue to read here

Condemned inmates seek info on lethal drug By Mike Ward, Austin Bureau : March 26, 2014

AUSTIN — Two condemned killers, including a one-time drifter who claimed he killed 70 people in a cross-country crime spree spanning 19 years, have sued state officials to force them to disclose details about the execution drugs that will be used to end their lives.
In a lawsuit filed in Travis County state court, Tommy Lynn Sells, 49, and Ramiro Hernandez Llanes, 44, alleged the Texas Department of Criminal Justice is illegally refusing to provide their attorneys with information about the powerful barbiturate pentobarbital that will be used to execute them, despite earlier court orders and attorney general opinions making that information available to them and the  public.
continue to read here

IACP Announces It is Tracking 61 pieces of legislation on behalf of IACP Members

IACP RX

MUST READ!! Weatherford Compounding Pharmacy Inspection Report from Texas Board of Pharmacy

read it here

CVM Updates FDA Receives Strong Industry Commitment for its Antibiotic Resistance Strategy

CVM Updates FDA Receives Strong Industry Commitment for its Antibiotic Resistance Strategy

Drug Products That Present Demonstrable Difficulties for Compounding Under Sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act; Request for Nominations--31 Comments Now Available for Public Viewing

null
  • See Attached
  • Public Submission
  • Posted:
    03/10/2014
  • ID:
    FDA-2013-N-1523-0008
  • Organization:
  • Submitter Name:


null
  • NOMINATION: Human Chorionic Gonadotropin (hCG) in any dosage form not injectable (i.e. it is "difficult to compound" hCG in oral, sublingual, intranasal, and topical delivery...
  • Public Submission
  • Posted:
    02/06/2014
  • ID:
    FDA-2013-N-1523-0002
  • Organization:
  • Submitter Name:

null
  • See Attached
  • Public Submission
  • Posted:
    03/07/2014
  • ID:
    FDA-2013-N-1523-0007
  • Organization:
  • Submitter Name:

null
  • See attached file(s)
  • Public Submission
  • Posted:
    03/21/2014
  • ID:
    FDA-2013-N-1523-0030
  • Organization:
  • Submitter Name:

null
  • See attached file(s)
  • Public Submission
  • Posted:
    03/21/2014
  • ID:
    FDA-2013-N-1523-0029
  • Organization:
  • Submitter Name:

null
  • See attached file(s)
  • Public Submission
  • Posted:
    03/21/2014
  • ID:
    FDA-2013-N-1523-0021
  • Organization:
  • Submitter Name:

Bulk Drug Substances That May Be Used to Compound Drug Products in Accordance With Section 503A of the Federal Food, Drug, and Cosmetic Act; Request for Nominations--Letters Posted so Far for Public Viewing

null
  • See Attached
  • Public Submission
  • Posted:
    03/07/2014
  • ID:
    FDA-2013-N-1525-0002
  • Organization:
  • Submitter Name:


FDA Issues Second 483 to Leiter's Cambrian Park Drugs, Inc. dba Leiter's Compounding Pharmacy, San Jose, CA

Leiter's Cambrian Park Drugs, Inc. (dba Leiter's Compounding Pharmacy), San Jose, CA

FDA Issues Second 483 to Wells Pharmacy Network LLC, Ocala, FL

Wells Pharmacy Network LLC, Ocala, FL

Recall on Bella Vi Dietary Supplement

03/26/2014Bella Vi  Dietary Supplement  Products contain undeclared Sibutramine and/or combination of Sibutramine and PhenolphthaleinPure Edge Nutrition, LLC

Consumer Updates FDA Partners With Veterinary Labs to Help Animals

Consumer Updates FDA Partners With Veterinary Labs to Help Animals

FDA to drugmakers: Tell doctors, patients not all drug approvals are permanent

  
 

By Virgil Dickson
Posted: March 25, 2014 - 3:00 pm ET

The Food and Drug Administration wants drugmakers to change labeling on drugs approved through the accelerated approval pathway so doctors and patients know such approvals could subsequently be revoked.

A new FDA guidance (PDF) seeks to clarify how drugs approved through the accelerated approval pathway should be labeled. The pathway in question is used to expedite the approval of medicines intended to treat serious or unmet needs. For instance, if there is a promising drug for a certain type of cancer that shows some early signs of benefit, that product could receive tentative accelerated approval.
continue to read here

Another Compounding Pharmacy Sales Rep Opening

Compounding Pharmacy Sales Rep-With Experience ONLY! (Hallandale)
compensation: Dependent on Experience
telecommuting okay
Compounding Pharmacy in South Florida searching for experienced sales person.
Candidate must have:
1. Experience selling sterile and non-sterile compounded medications
2. Background in Anti-Aging, Hormone Replacement, Pain Management, Dermatology, Erectile Dysfunction
3. Able to travel if necessary and manage clients remotely (through technology)
4. Fluent in English (and Spanish a plus but not required)

Serious Candidates only!
Send by email Resume with "position-your name" in email subject line.
  • Principals only. Recruiters, please don't contact this job poster.
  • do NOT contact us with unsolicited services or offers
post id: 4391746346
posted:
updated:

Look at all the Compounding topics to be covered at the 110th Annual NABP Meeting

read about it here

Must Read! Been There Done It Post on Horse Doping--very telling information

read here

Interesting Blog Post on the horse doping scandal--the mushy middle

read here

Tuesday, March 25, 2014

FDA Recall on Super Fat Burner, Maxi Gold and Esmeralda

03/25/2014Super Fat Burner, Maxi Gold, and Esmeralda  Dietary Supplement  Unapproved new drugNew Life Nutritional CenterSelect to View Firm Press Release

The Ugly Truth About Horse Racing

The Ugly Truth About Horse Racing

An exposé by PETA, published in The New York Times, shows a side of the sport that the industry has tried hard to shield from public view. 

Tom Noonan--Yet Another Wake Up Call for Horse Racing

Posted in: Horse Racing, Political/Social commentary, Politics. Tagged: , , , , , , , , . Leave a comment
Racing at Saratoga brings many of the nation’s best horses, trainers and jockeys to the Spa for a 40-day meet in a resort atmosphere.  It also brings industry leaders who participate in the several seminars that take place.  Last year the unifying theme may well have been drugs and the public’s perception of widespread abuse.
At one such session last year, trainer John Kimmel lambasted those who thought that mistreatment of horses was a problem, blaming it on  -  wait for it  -  the media.  He challenged them to go to the backstretch to observe how well the horses are cared for.  Little did he know that as he was speaking, someone was doing just that, armed with a video camera.  This week, the work of the undercover investigator for PETA (People for the Ethical Treatment of Animals) became public courtesy of Joe Drape of The New York Times and PETA’s web site.
According to Drape’s piece, the investigator worked in Steve Asmussen’s barn at Churchill Downs and Saratoga for four months.  It is clear no one was aware they were being recorded.  PETA has filed complaints with ten federal and state agencies based on the investigation, but it is a nine-minute video that has the racing world abuzz.  Among PETA’s allegations are the mistreatment of horses, the use of batteries to shock horses, administration of Lasix as a performance-enhancing drug, and numerous violations of employment laws
read here

Thought, feelings, observations on Asumussen video scandal

Thought, feelings, observations on Asumussen video scandal

Clean up ‘chemical’ horse racing

It’s time for the U.S. Anti-Doping Agency to step in and clean up the thoroughbred racing industry’s addiction to drugs.
As The New York Times has just reported, over a period of four months, a PETA investigator worked for well-known trainer Steve Asmussen, trainer of Curlin and Rachel Alexandra, at two of the most famous racetracks in America: Churchill Downs in Kentucky and the Saratoga Race Course in New York. PETA’s investigation exposed many serious problems but none more harmful than the routine, pervasive and improper use of prescription drugs during training, a regimen that has begun the downward spiral to the slaughterhouse for thousands of horses.
Fragile young horses — raced before their bones have fully matured and unable to handle the pounding and stress — suffer routinely from injuries, lameness, exhaustion and what is euphemistically called "soreness." Owners don’t want to waste time waiting until foals are physically capable. They want to get the cash flow started.
continue to read here

FDA approves J&J to make bulk Doxil at closed Ben Venue plant

Janssen has another manufacturer finish off the drug as part of an 'alternative' process


Read more: FDA approves J&J to make bulk Doxil at closed Ben Venue plant - FiercePharma Manufacturing http://www.fiercepharmamanufacturing.com/story/fda-approves-jj-make-bulk-doxil-closed-ben-venue-plant/2014-03-25#ixzz2x09NMNZN
Subscribe at FiercePharma Manufacturing

Hospira CEO gets nearly $10M for steering drugmaker through issues

Pharmacy Law Blog: Out-of-State Compounding Pharmacies May Need a Permit To Do Business in Florida By Lance O. Leider, J.D., The Health Law Firm

read here

Pharmacists Urged Not to Assist US Executions

Several human rights and anti-death penalty groups have asked the American Pharmacists Association to prohibit members from participating in executions, a request that comes as states increasingly turn to pharmacists for lethal injection drugs.
The groups, which include Amnesty International, the NAACP and the American Civil Liberties Union, are targeting so-called compounded drugs. Such drugs, which are not federally regulated, are individually mixed versions of medications that prison systems are finding increasingly difficult to obtain.
Death  penalty opponents say such drugs put inmates at risk of pain and suffering. Two years ago, an outbreak of meningitis that killed 64 and sickened hundreds was traced to a compounding facility in Massachusetts.
Pharmacists who provide compounded drugs are violating key provisions of the pharmacists' association code of ethics, including helping patients achieve "optimum benefit" from their medications, according to a letter the death penalty opponents presented to the association on Monday.
continue to read here

Tennessee board adds new rules for compounding pharmacies

Tennessee board adds new rules for compounding pharmacies

Florida House committee passes bill regulating compounding pharmacies

read here

Warning Letters Smruthi Organics Limited 3/6/14

Warning Letters Smruthi Organics Limited 3/6/14