Tuesday, August 5, 2014

Alan Madison: A Prescription for Patient Safety When Using Compounded Medications--author points out history of compounded drugs causing fatalities has driven need for legislation even in 1901

In this day when almost anything can be customized, tailoring a prescription to meet an individual’s need for a specific dosage or delivery system might make sense—but in the wake of recent headlines it probably pays to proceed cautiously with compound medications. Although only a small percentage of an employer’s workers’ compensation pharmacy spend is allocated to compounded medications, the potential for human harm is great.
Tragedies mark need for oversight
Throughout much of history, most remedies were compounded. The forerunners of today’s pharmacists mixed and dispensed plants and other natural ingredients and, later, chemicals. Mass production of medications didn’t start to come into play until the 1800s. In 1901, 13 children in St. Louis, Missouri, died of tetanus after they received shots of contaminated diphtheria antitoxin; nine more died in Camden, New Jersey. Those fatalities drove the passage of the Biologics Control Act of 1902—among the first regulations designed to address drug production in order to protect the public health.

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