Textbook of Veterinary Internal Medicine Points Out that vast majority of veterinary compounds lack adequate pharmaceutical and clinical testing: Before buying veterinary compounds ask the pharmacist or veterinarian if the compounds have been test and what test have been conducted.

UNDERSTANDING RISKS VERSUS BENEFITS WITH COMPOUNDED DRUGS


Pharmaceutical Issues

Compounding by medical professionals and pharmacists is not equivalent to the formulation of commercially manufactured products by reputable pharmaceutical firms. Drug formulation requires an understanding of the physical and chemical characteristics of the active pharmaceutical ingredient, along with the other agents (e.g., vehicles, excipients) used to produce the administered dosage form, in order to maintain the administered drug's effectiveness and safety profile. To this end, a compounded drug must possess adequate purity, potency, and demonstrate stability (shelf life) to maintain acceptable bioavailability (extent of systemic drug absorption) of the active pharmaceutical ingredient, but not produce toxicity or an ineffective preparation. However, for the vast majority of drugs compounded by veterinarians and most pharmacists, there is a lack of adequate pharmaceutical and clinical testing to ensure …
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